Reports: Cardinals rolling with Jacoby Brissett again as Kyler Murray is out

Field Level Media|published: Sat 18th October, 14:57 2025

Arizona Cardinals quarterback Jacoby Brissett (7) looks to throw while Indianapolis Colts defensive tackle Grover Stewart (90) and defensive tackle Neville Gallimore (92) attempt to bring him down during a game on Sunday, Oct. 12, 2025, at Lucas Oil Stadium in Indianapolis. The Colts defeated the Cardinals 31-27.

The Arizona Cardinals are planning to turn to backup quarterback Jacoby Brissett for another week as Kyler Murray sits out with his foot injury again, NFL Network reported Saturday.

Murray, 28, has been dealing with a high-foot sprain since he sustained an injury during the Cardinals' Week 5 22-21 loss to the Tennessee Titans. After practicing just one day before last week's game against the Indianapolis Colts, Murray was limited in practice throughout this week before he was listed as questionable on Friday's injury report.

The move may have been anticipated as Brissett was seen practicing with the starters throughout the week.

Brissett kept the Cardinals in the game last week, before ultimately falling 31-27 to the Colts. He finished the game 27-of-44 passing for 320 yards, two touchdowns and an interception.

The Cardinals and Brissett will shift their focus to the Green Bay Packers this weekend. Brissett will aim to get Arizona its first win over Green Bay since 2018.

--Field Level Media

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